Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.770

The method score is based on:

Property Details
Experiments 16519508, 12551948, 29382714, 16519507, 22965877, 21985244, 19014373, 19527721, 17078951, 12048243, 17045592, 9614189, 9735171, 16446437, 15542598, 18467332, 15073173, 16365045, 14612456, 9771888 and 8 others

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Identification Methods affinity chromatography technology, pull down, enzymatic study, anti tag coimmunoprecipitation, protein kinase assay
Interaction Type physical association, direct interaction, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 8 others

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Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 758
Hs

1 420
+ Hs
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Bt
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024