HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: GNAQ (P50148)
Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q)
Gene: GNAQ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 359
+	Hs
		496380 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNA11_HUMAN (1-359): 6.04e-170: 479: 90.25
+	Hs
		496793 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNAI1_HUMAN (7-358): 4.95e-168: 474: 52.26
+	Hs
		450973 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNAO_HUMAN (7-358): 2.12e-167: 472: 50.57
+	Hs
		391314 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNAI2_HUMAN (7-358): 4.08e-166: 469: 50.42
+	Hs
		444653 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNAI3_HUMAN (7-358): 3.79e-165: 467: 51.13
+	Hs
		325959 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNA14_HUMAN (9-359): 4.99e-163: 461: 81.77
+	Mm
		497926 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GNAQ_MOUSE (1-359): 2.21e-175: 492: 99.72
+	Hs
		497017 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNA13_HUMAN (8-358): 7.06e-152: 434: 45.56
+	Rn
		581959 TAU_RAT (1-758): 4.86e-75: 260: 71.47		GNAO_RAT (7-358): 1.2e-165: 468: 49.72
+	Rn
		94182 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		GNAO_RAT (7-358): 1.2e-165: 468: 49.72
+	Hs
		496266 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNAZ_HUMAN (7-358): 2.4e-150: 429: 47.89
+	Mm
		497925 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GNA11_MOUSE (1-359): 3.22e-171: 482: 89.14
+	Hs
		496792 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GNAS2_HUMAN (7-359): 1e-148: 426: 38.07
+	Mm
		70618 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GNAI1_MOUSE (7-358): 4.95e-168: 474: 52.26
+	Mm
		444631 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GNAI2_MOUSE (7-358): 1.16e-164: 465: 50.42
+	Mm
		250846 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GNAZ_MOUSE (7-358): 5.44e-151: 431: 48.17