HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 216
+	Hs
		497392 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB8B_HUMAN (15-211): 6.32e-97: 282: 38.19
+	Hs
		496764 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1A_HUMAN (12-214): 1.9e-93: 273: 41.18
+	Hs
		497581 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1B_HUMAN (14-214): 1.47e-90: 265: 40.30
+	Hs
		496282 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		496695 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB5B_HUMAN (1-216): 1.1e-87: 259: 84.26
+	Hs
		496754 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		497091 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89
+	Mm
		497936 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB5C_MOUSE (1-216): 3.24e-94: 275: 98.61
+	Mm
		497979 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1A_MOUSE (12-214): 1.9e-93: 273: 41.18
+	Mm
		498121 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB5A_MOUSE (1-216): 2.84e-90: 265: 87.04
+	Mm
		498132 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1B_MOUSE (14-214): 1.85e-90: 265: 40.30
+	Hs
		497774 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB22A_HUMAN (21-214): 1.25e-61: 192: 47.94
+	Hs
		497651 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB6B_HUMAN (16-213): 8.99e-53: 170: 41.71
+	Hs
		496283 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB6A_HUMAN (16-213): 2.31e-51: 166: 40.59
+	Mm
		497966 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB6B_MOUSE (16-213): 8.99e-53: 170: 41.71
+	Hs
		592112 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Mm
		649199 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		RB22A_MOUSE (21-214): 3.87e-61: 191: 47.42