HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PLCD1 (P51178)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-1) (Phospholipase C-III) (PLC-III) (Phospholipase C-delta-1) (PLC-delta-1)
Gene: PLCD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 756
+	Hs
		497050 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PLCB4_HUMAN (16-755): 0: 722: 29.80
+	Hs
		497635 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PLCB1_HUMAN (9-756): 0: 708: 29.07
+	Hs
		496268 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PLCG1_HUMAN (478-754): 4.91e-75: 266: 36.56
+	Hs
		496239 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PLCG2_HUMAN (444-755): 2.83e-69: 249: 29.91
+	Hs
		580935 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		PLCG1_HUMAN (478-754): 4.91e-75: 266: 36.56
+	Dm
		632600 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		PIP1_DROME (479-756): 2.5e-70: 253: 35.11