HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: NOVA1 (P51513)
RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1)
Gene: NOVA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 507
+	Hs
		497805 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NOVA2_HUMAN (19-507): 5.49e-85: 272: 66.80
+	Hs
		496726 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRPK_HUMAN (8-498): 2.04e-75: 246: 18.70
+	Hs
		497065 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PCBP2_HUMAN (37-501): 4.26e-66: 219: 20.86
+	Hs
		497064 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PCBP1_HUMAN (37-497): 5.55e-65: 216: 19.74
+	Mm
		497970 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		HNRPK_MOUSE (8-498): 2.04e-75: 246: 18.70
+	Hs
		128005 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IF2B3_HUMAN (2-507): 2.23e-50: 183: 18.31
+	Mm
		497959 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		PCBP1_MOUSE (37-497): 5.55e-65: 216: 19.74
+	Hs
		497393 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FUBP2_HUMAN (322-498): 2.06e-11: 68.5: 15.43
+	Hs
		497692 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IF2B1_HUMAN (237-495): 1.75e-10: 65.4: 15.30
+	Hs
		497407 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FUBP1_HUMAN (393-500): 9.46e-10: 63.1: 23.15
+	Hs
		653982 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		PCBP1_HUMAN (37-497): 5.55e-65: 216: 19.74
+	Mm
		497957 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		PCBP3_MOUSE (3-123): 6.02e-12: 69.3: 23.39
+	Mm
		498053 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		PCBP2_MOUSE (27-129): 5.88e-11: 66.2: 19.42
+	Hs
		1056915 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		FUBP2_HUMAN (322-498): 2.06e-11: 68.5: 15.43
+	Hs
		1056922 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		FUBP1_HUMAN (393-500): 9.46e-10: 63.1: 23.15
+	Ce
		90332 UNC89_CAEEL (4-459): 4.47e-21: 101: 12.37		E0R7K7_CAEEL (160-252): 9.11e-09: 58.9: 36.08