HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: IMA1 (P52292)
Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha)
Gene: KPNA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 529
+	Hs
		134829 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38
+	Hs
		131372 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA4_HUMAN (4-529): 6.93e-148: 436: 49.06
+	Hs
		238627 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA7_HUMAN (1-528): 1.97e-141: 420: 45.37
+	Hs
		168613 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA6_HUMAN (1-528): 9.99e-138: 410: 45.02
+	Hs
		496611 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47