HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36634849
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030425 - dendrite
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 538
+	Hs
		238627 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48
+	Hs
		134829 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA3_HUMAN (1-538): 7e-156: 456: 45.84
+	Hs
		168613 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59
+	Hs
		131372 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91
+	Hs
		496610 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36