HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: HNRPF (P52597)
Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed]
Gene: HNRNPF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 415
+	Hs
		496179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66
+	Hs
		496413 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82
+	Rn
		582032 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PABP1_RAT (1-410): 5.31e-80: 260: 13.66
+	Rn
		94258 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PABP1_RAT (1-410): 5.31e-80: 260: 13.66
+	Hs
		496661 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRH2_HUMAN (1-413): 9.35e-67: 220: 72.40
+	Mm
		498054 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q62029_MOUSE (1-410): 4.07e-77: 252: 14.62
+	Hs
		496957 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP4_HUMAN (3-299): 6.9e-46: 169: 12.17
+	Hs
		201653 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MSI1H_HUMAN (93-302): 4.72e-16: 81: 14.09
+	Hs
		496346 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV4_HUMAN (264-365): 1.01e-12: 71.1: 11.43
+	Hs
		496269 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NUCL_HUMAN (75-370): 1.39e-11: 68.3: 19.21
+	Hs
		496937 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV2_HUMAN (273-365): 1.16e-11: 67.6: 11.46
+	Hs
		496412 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRH3_HUMAN (13-86): 4.01e-11: 66: 39.19
+	Hs
		516595 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66
+	Mm
		498050 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ELAV4_MOUSE (264-365): 1.2e-12: 70.7: 11.43
+	Hs
		582292 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		NUCL_HUMAN (75-370): 1.39e-11: 68.3: 19.21
+	Hs
		582417 PRG4_HUMAN (4-604): 5.21e-20: 97.8: 8.93		NUCL_HUMAN (75-370): 1.39e-11: 68.3: 19.21
+	Dm
		1366083 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VGH5_DROME (9-86): 8.35e-11: 65.6: 34.62