HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TXTP (P53007)
Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Mitochondrial citrate carrier) (CIC) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein)
Gene: SLC25A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36634849, 35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 311
+	Hs
		397240 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ADT2_HUMAN (116-310): 3.42e-36: 133: 23.67
+	Hs
		496183 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ADT1_HUMAN (115-309): 1.18e-35: 131: 22.22
+	Hs
		496184 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ADT3_HUMAN (121-310): 2.98e-35: 131: 22.28
+	Hs
		497760 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S2513_HUMAN (1-117): 7.19e-25: 106: 26.89
+	Hs
		497605 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GHC1_HUMAN (21-297): 1.35e-25: 105: 27.42
+	Rn
		581991 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ADT1_RAT (115-309): 5.96e-36: 132: 23.19
+	Rn
		581994 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ADT2_RAT (116-310): 8.71e-36: 132: 23.19
+	Rn
		94213 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ADT1_RAT (115-309): 5.96e-36: 132: 23.19
+	Rn
		94216 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ADT2_RAT (116-310): 8.71e-36: 132: 23.19
+	Hs
		274476 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S2512_HUMAN (224-307): 3.08e-20: 93: 29.67
+	Mm
		497947 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ADT1_MOUSE (115-309): 5.66e-36: 133: 23.19
+	Mm
		497951 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ADT2_MOUSE (116-310): 6.91e-36: 132: 23.19
+	Mm
		498134 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GHC1_MOUSE (21-297): 1.67e-25: 105: 28.01
+	Mm
		498076 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		S2512_MOUSE (224-307): 1.55e-20: 93.7: 30.77
+	Hs
		1056992 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		GHC1_HUMAN (21-297): 1.35e-25: 105: 27.42