HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: AP3M2 (P53677)
AP-3 complex subunit mu-2 (Adaptor-related protein complex 3 subunit mu-2) (Clathrin assembly protein assembly protein complex 3 mu-2 medium chain) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Mu3B-adaptin) (P47B)
Gene: AP3M2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:1904115 - axon cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 418
+	Hs
		497548 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AP1M1_HUMAN (2-418): 2.99e-166: 474: 25.81
+	Hs
		497844 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AP3M1_HUMAN (1-418): 8.75e-165: 471: 84.21
+	Hs
		497422 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AP2M1_HUMAN (1-417): 6.29e-151: 436: 24.89
+	Rn
		581982 TAU_RAT (1-758): 4.86e-75: 260: 71.47		AP2M1_RAT (1-417): 6.29e-151: 436: 24.89
+	Rn
		94205 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		AP2M1_RAT (1-417): 6.29e-151: 436: 24.89
+	Mm
		498008 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		AP2M1_MOUSE (1-417): 6.29e-151: 436: 24.89
+	Hs
		654028 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		AP2M1_HUMAN (1-417): 6.29e-151: 436: 24.89
+	Dm
		248311 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		O62530_DROME (1-417): 4.66e-148: 429: 24.44
+	Hs
		203244 SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76		AP2M1_HUMAN (1-417): 6.29e-151: 436: 24.89
+	Hs
		496542 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		COPD_HUMAN (7-157): 7.48e-18: 87.4: 9.87