HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: SEC13 (P55735)
Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein)
Gene: SEC13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 322
+	Hs
		496503 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		LIS1_HUMAN (208-320): 5.26e-24: 102: 20.35
+	Hs
		497427 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SEH1_HUMAN (15-180): 2.01e-09: 60: 18.75
+	Hs
		654026 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72
+	Hs
		152678 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72
+	Hs
		152663 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5B_HUMAN (2-194): 1.22e-31: 122: 16.67
+	Hs
		1281391 PRR36_HUMAN (1-607): 1.27e-15: 83.6: 10.11		FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72
+	Hs
		1056932 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22
+	Hs
		653951 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67
+	Hs
		152622 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67
+	Mm
		903669 KMT2C_MOUSE (228-587): 6.06e-09: 61.9: 16.84		WDR5_MOUSE (249-320): 1.4e-10: 63.3: 16.67
+	Hs
		903374 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		WDR5_HUMAN (249-320): 1.4e-10: 63.3: 16.67