Interactor 1: IRGM (A1A4Y4)
Immunity-related GTPase family M protein (EC 3.6.5.-) (Immunity-related GTPase family M protein 1) (Interferon-inducible protein 1) (LPS-stimulated RAW 264.7 macrophage protein 47 homolog) (LRG-47)
Gene: IRGM

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.55 0.458

The method score is based on:

Property Details
Experiments 25891078
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000045 - autophagosome assembly
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0010508 - positive regulation of autophagy
GO:1901526 - positive regulation of mitophagy
Homologous interactions 0

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Last updated: 15 Jul 2024