HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 449
+	Hs
		496957 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59
+	Hs
		496179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29
+	Hs
		496413 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21
+	Rn
		582032 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PABP1_RAT (1-448): 5.59e-81: 264: 12.29
+	Rn
		94258 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PABP1_RAT (1-448): 5.59e-81: 264: 12.29
+	Hs
		496614 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72
+	Mm
		498054 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q62029_MOUSE (1-448): 9.75e-78: 255: 12.79
+	Hs
		496412 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRH3_HUMAN (10-86): 8.49e-10: 62.2: 33.77
+	Hs
		496269 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16
+	Mm
		449409 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		NUCL_MOUSE (5-247): 9.36e-16: 81.8: 19.92
+	Hs
		516595 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29
+	Hs
		582292 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16
+	Hs
		582417 PRG4_HUMAN (4-604): 5.21e-20: 97.8: 8.93		NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16
+	Dm
		1366083 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VGH5_DROME (113-184): 3.71e-10: 64: 31.94