HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 19895707, 26269332, 21339331, 35063084
Identification Methods pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0019901 - protein kinase binding
and 2 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 758
Hs

1 375
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+ Mm
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+ Ce
+ Ce
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+ Ce
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+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024