HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: S10AA (P60903)
Protein S100-A10 (Calpactin I light chain) (Calpactin-1 light chain) (Cellular ligand of annexin II) (S100 calcium-binding protein A10) (p10 protein) (p11)
Gene: S100A10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 97
+	Hs
		497264 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HORN_HUMAN (1-97): 6.55e-32: 118: 30.69
+	Hs
		496312 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10A1_HUMAN (1-91): 7.71e-34: 113: 45.75
+	Hs
		497147 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FILA2_HUMAN (3-97): 5.92e-28: 107: 34.34
+	Hs
		416341 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10A9_HUMAN (3-96): 8.76e-29: 101: 29.59
+	Hs
		380723 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S100B_HUMAN (3-87): 2.3e-26: 94.6: 37.50
+	Hs
		497435 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10AG_HUMAN (3-96): 6.44e-26: 93.8: 23.47
+	Hs
		396671 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10A8_HUMAN (1-93): 1.69e-23: 87.6: 25.00
+	Hs
		416558 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10A6_HUMAN (1-88): 2.47e-23: 86.9: 25.28
+	Hs
		496287 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FILA_HUMAN (1-97): 2.57e-20: 85.7: 26.73
+	Hs
		497487 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10AD_HUMAN (3-81): 1.23e-18: 75.3: 30.49
+	Hs
		152595 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		S10A2_HUMAN (1-87): 6.38e-28: 98.8: 36.67
+	Bt
		361268 TAU_BOVIN (1-291): 3.66e-12: 71.3: 40.00		S100B_BOVIN (3-87): 8.22e-27: 95.7: 36.36