HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RAB2A (P61019)
Ras-related protein Rab-2A (EC 3.6.5.2)
Gene: RAB2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	32812023, 26269332, 35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 212
+	Hs
		497392 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB8B_HUMAN (2-199): 1.31e-94: 276: 45.46
+	Hs
		496764 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1A_HUMAN (3-212): 3.93e-84: 249: 45.24
+	Hs
		496701 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB14_HUMAN (3-211): 2.23e-83: 248: 58.85
+	Hs
		496754 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67
+	Hs
		497091 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB11B_HUMAN (3-212): 1.54e-82: 246: 47.62
+	Hs
		497581 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1B_HUMAN (3-212): 7.6e-83: 246: 44.29
+	Hs
		496281 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB4A_HUMAN (3-188): 6.91e-72: 219: 57.53
+	Mm
		497979 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1A_MOUSE (3-212): 3.93e-84: 249: 45.24
+	Hs
		108975 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		H0YNE9_HUMAN (3-171): 3.56e-61: 191: 50.89
+	Mm
		498132 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1B_MOUSE (3-212): 1.1e-82: 245: 43.81