HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RAB5B (P61020)
Ras-related protein Rab-5B (EC 3.6.5.2)
Gene: RAB5B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 215
+	Hs
		496764 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1A_HUMAN (10-213): 8.59e-91: 266: 39.51
+	Hs
		496282 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB5A_HUMAN (1-215): 9.46e-89: 262: 81.86
+	Hs
		497581 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1B_HUMAN (13-213): 4.44e-89: 262: 39.30
+	Hs
		496592 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB5C_HUMAN (1-215): 7.24e-88: 259: 84.26
+	Hs
		496754 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61
+	Hs
		497091 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB11B_HUMAN (10-215): 3.73e-85: 252: 39.63
+	Mm
		497979 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1A_MOUSE (10-213): 8.59e-91: 266: 39.51
+	Mm
		498121 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB5A_MOUSE (1-215): 1.96e-89: 263: 81.86
+	Mm
		498132 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1B_MOUSE (13-213): 7.51e-89: 261: 39.30
+	Mm
		497936 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB5C_MOUSE (1-215): 5.16e-88: 260: 84.26
+	Hs
		497774 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB22A_HUMAN (20-213): 7.44e-62: 192: 47.94
+	Hs
		497651 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB6B_HUMAN (20-185): 5.86e-49: 160: 45.78
+	Mm
		497966 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB6B_MOUSE (20-185): 5.86e-49: 160: 45.78
+	Hs
		592112 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		RAB5A_HUMAN (1-215): 9.46e-89: 262: 81.86
+	Mm
		649199 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		RB22A_MOUSE (20-213): 3.7e-62: 193: 47.94