HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 443
+	Hs
		121669 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PSD11_HUMAN (35-442): 5.44e-89: 278: 22.43
+	Hs
		497037 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PSMD6_HUMAN (55-440): 4.29e-87: 272: 13.01
+	Hs
		121920 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PSD12_HUMAN (39-440): 8.69e-83: 263: 12.80
+	Hs
		496946 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02
+	Hs
		497525 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25
+	Rn
		582015 TAU_RAT (1-758): 4.86e-75: 260: 71.47		CSN4_RAT (54-440): 2.96e-70: 229: 16.29
+	Rn
		94241 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		CSN4_RAT (54-440): 2.96e-70: 229: 16.29