HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: COPZ1 (P61923)
Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP)
Gene: COPZ1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 177
+	Hs
		497365 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AP3S1_HUMAN (13-172): 7.45e-54: 171: 22.02
+	Hs
		496667 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AP1S2_HUMAN (13-157): 9.56e-46: 149: 18.37
+	Hs
		496627 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AP2S1_HUMAN (13-153): 5.58e-45: 146: 19.58
+	Mm
		498140 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		AP3S1_MOUSE (13-172): 7.45e-54: 171: 22.02
+	Mm
		592762 MTAP2_MOUSE (26-758): 1.71e-30: 131: 23.89		AP2S1_MOUSE (13-153): 5.58e-45: 146: 19.58
+	Mm
		649203 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		AP2S1_MOUSE (13-153): 5.58e-45: 146: 19.58