HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005576 - extracellular region GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 103
+	Rn
		581967 TAU_RAT (1-758): 4.86e-75: 260: 71.47		H4_RAT (1-103): 1.38e-48: 151: 100.00
+	Rn
		94190 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		H4_RAT (1-103): 1.38e-48: 151: 100.00
+	Mm
		497978 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		H4_MOUSE (1-103): 1.38e-48: 151: 100.00
+	Hs
		917267 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		152623 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917476 SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917621 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		H4_HUMAN (1-103): 1.38e-48: 151: 100.00