HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RAB1A (P62820)
Ras-related protein Rab-1A (EC 3.6.5.2) (YPT1-related protein)
Gene: RAB1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 205
+	Hs
		497392 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB8B_HUMAN (4-203): 8.94e-88: 258: 52.00
+	Hs
		497581 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08
+	Hs
		496754 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB11A_HUMAN (1-205): 3.52e-83: 247: 44.60
+	Hs
		497091 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB11B_HUMAN (1-205): 1.3e-81: 243: 44.19
+	Hs
		496701 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86
+	Hs
		108975 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		H0YNE9_HUMAN (4-176): 3.99e-75: 226: 59.54
+	Mm
		497979 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1A_MOUSE (1-205): 4.45e-92: 269: 100.00
+	Mm
		498132 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1B_MOUSE (4-205): 1e-85: 253: 91.09