HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.585

Property	Details
Experiments	14612456, 35063084
Identification Methods	enzymatic study, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 147
+	Hs
		496697 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UB2D3_HUMAN (1-147): 1.54e-81: 238: 97.28
+	Hs
		496700 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22
+	Dm
		973539 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		Q9VQ00_DROME (2-146): 1.45e-71: 213: 57.24