HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PPIA (P62937)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 165
+	Hs
		496920 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PPID_HUMAN (2-165): 3.38e-88: 263: 59.30
+	Hs
		496311 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PPIB_HUMAN (2-165): 9.46e-88: 257: 63.64
+	Rn
		486006 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PPIA_RAT (1-164): 1.43e-89: 260: 96.34
+	Rn
		94126 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PPIA_RAT (1-164): 1.43e-89: 260: 96.34
+	Mm
		497927 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		PPIB_MOUSE (2-165): 4.68e-87: 255: 62.42
+	Hs
		554273 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		PPIF_HUMAN (3-164): 6.26e-92: 267: 76.54
+	Hs
		152624 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00