HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: FKB1A (P62942)
Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase)
Gene: FKBP1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.585

Property	Details
Experiments	30382094, 35063084
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0097435 - supramolecular fiber organization GO:1990000 - amyloid fibril formation
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 108
+	Hs
		496352 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FKBP2_HUMAN (1-108): 1.24e-50: 158: 44.44
+	Hs
		496862 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FKBP3_HUMAN (5-108): 5.68e-42: 138: 40.18
+	Hs
		496884 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FKBP4_HUMAN (2-108): 1.57e-15: 72.4: 27.03
+	Hs
		496969 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FKBP5_HUMAN (2-108): 3.73e-15: 71.3: 28.44
+	Rn
		582038 TAU_RAT (1-758): 4.86e-75: 260: 71.47		FKBP4_RAT (2-108): 3.17e-15: 71.3: 27.93