HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: UB2L3 (P68036)
Ubiquitin-conjugating enzyme E2 L3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L3) (L-UBC) (UbcH7) (Ubiquitin carrier protein L3) (Ubiquitin-conjugating enzyme E2-F1) (Ubiquitin-protein ligase L3)
Gene: UBE2L3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019899 - enzyme binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 154
+	Hs
		496768 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UB2D2_HUMAN (2-149): 7.95e-75: 221: 37.58
+	Hs
		496697 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UB2D3_HUMAN (2-149): 8.29e-74: 218: 36.91
+	Hs
		497630 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UBE2T_HUMAN (43-151): 2.92e-25: 97.1: 40.18
+	Dm
		973539 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		Q9VQ00_DROME (2-151): 5.94e-67: 202: 35.76