HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19895707
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0044297 - cell body
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 377
+	Hs
		496683 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		496806 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		496813 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		496759 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ACTA_HUMAN (1-377): 0: 602: 97.88
+	Mm
		498001 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ACTC_MOUSE (1-377): 0: 604: 98.94
+	Hs
		503276 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		932156 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Ce
		501479 Q95QG4_CAEEL (411-693): 9.33e-25: 110: 29.33		ACT4_CAEEL (1-377): 0: 607: 94.16
+	Hs
		554290 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		ACTA_HUMAN (1-377): 0: 602: 97.88
+	Ce
		109402 H2KY94_CAEEL (465-688): 3.39e-25: 107: 33.48		ACT4_CAEEL (1-377): 0: 607: 94.16
+	Ce
		137705 O02592_CAEEL (353-709): 5.66e-13: 73.8: 21.29		ACT4_CAEEL (1-377): 0: 607: 94.16
+	Hs
		891853 SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		929905 SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		932219 SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Dm
		501445 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		ACT5_DROME (1-377): 0: 603: 93.37
+	Hs
		203220 SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76		ACTC_HUMAN (1-377): 0: 604: 98.94