HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TBA4A (P68366)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)
Gene: TUBA4A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.683

The method score is based on:

Property Details
Experiments 19681044, 35063084, 24251416, 26269332
Identification Methods pull down, affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000226 - microtubule cytoskeleton organization
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005874 - microtubule
and 2 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 758
Hs

1 448
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Rn
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024