HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CXAR (P78310)
Coxsackievirus and adenovirus receptor (CAR) (hCAR) (CVB3-binding protein) (Coxsackievirus B-adenovirus receptor) (HCVADR)
Gene: CXADR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030426 - growth cone GO:0043005 - neuron projection and 2 others more... GO:0044297 - cell body GO:0045121 - membrane raft
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 365
+	Hs
		497706 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NTRI_HUMAN (1-312): 4.68e-50: 172: 18.94
+	Hs
		497622 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROBO2_HUMAN (1-364): 3.87e-45: 167: 13.58
+	Hs
		497543 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		JAM3_HUMAN (18-296): 2.7e-46: 162: 18.79
+	Hs
		497034 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HECAM_HUMAN (9-362): 3.64e-44: 159: 18.53
+	Hs
		497238 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NEGR1_HUMAN (27-318): 5.18e-44: 157: 16.56
+	Hs
		497905 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROBO1_HUMAN (11-345): 1.8e-35: 139: 14.00
+	Hs
		311038 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MPZL1_HUMAN (17-154): 1.8e-37: 137: 30.44
+	Hs
		497387 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NEO1_HUMAN (20-365): 3.15e-28: 118: 13.86
+	Hs
		497385 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NRCAM_HUMAN (1-365): 3.3e-22: 100: 11.03
+	Hs
		497174 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CD276_HUMAN (2-239): 6.28e-21: 96.1: 20.72
+	Hs
		297826 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00
+	Hs
		497357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TITIN_HUMAN (10-144): 8.96e-09: 59.6: 15.56
+	Hs
		1056924 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		ESAM_HUMAN (3-365): 4.67e-54: 184: 23.59