HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RBM6 (P78332)
RNA-binding protein 6 (Lung cancer antigen NY-LU-12) (Protein G16) (RNA-binding motif protein 6) (RNA-binding protein DEF-3)
Gene: RBM6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1123
+	Hs
		496850 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RBM10_HUMAN (184-1121): 8.07e-114: 377: 18.70
+	Hs
		496616 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RBM5_HUMAN (417-1123): 5.16e-111: 367: 24.45
+	Hs
		496269 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NUCL_HUMAN (379-743): 8.76e-67: 241: 17.81
+	Hs
		958026 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		RBM10_HUMAN (184-1121): 8.07e-114: 377: 18.70
+	Mm
		449409 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		NUCL_MOUSE (379-743): 1.39e-63: 232: 16.99
+	Hs
		496957 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP4_HUMAN (329-542): 5.81e-29: 126: 11.22
+	Hs
		496179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP1_HUMAN (329-542): 1.32e-28: 124: 10.75
+	Rn
		582032 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PABP1_RAT (329-542): 7.03e-29: 126: 10.75
+	Rn
		94258 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PABP1_RAT (329-542): 7.03e-29: 126: 10.75
+	Hs
		275786 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		EIF3G_HUMAN (528-743): 3.25e-13: 73.8: 18.64
+	Hs
		446492 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SNRPA_HUMAN (451-740): 3.38e-13: 73.4: 13.65
+	Hs
		582292 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		NUCL_HUMAN (379-743): 8.76e-67: 241: 17.81
+	Mm
		498054 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q62029_MOUSE (332-665): 6.72e-27: 119: 10.66
+	Hs
		582417 PRG4_HUMAN (4-604): 5.21e-20: 97.8: 8.93		NUCL_HUMAN (379-743): 8.76e-67: 241: 17.81
+	Hs
		516595 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		PABP1_HUMAN (329-542): 1.32e-28: 124: 10.75