HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	35063084, 26269332
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1675
+	Rn
		509757 TAU_RAT (1-758): 4.86e-75: 260: 71.47		CLH1_RAT (1-1675): 0: 3123: 99.76
+	Rn
		94130 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		CLH1_RAT (1-1675): 0: 3123: 99.76
+	Mm
		498059 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		CLH1_MOUSE (1-1675): 0: 3131: 99.88
+	Hs
		203221 SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Dm
		669626 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		CLH_DROME (1-1663): 0: 2911: 80.17