HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PFKAP (Q01813)
ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase)
Gene: PFKP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	32812023, 35063084
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 784
+	Hs
		437708 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Rn
		581947 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PFKAP_RAT (15-780): 0: 1034: 89.82
+	Rn
		94171 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PFKAP_RAT (15-780): 0: 1034: 89.82
+	Mm
		498160 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		PFKAP_MOUSE (15-780): 0: 1046: 90.21
+	Rn
		581946 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PFKAM_RAT (13-779): 0: 1014: 71.52
+	Rn
		94170 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PFKAM_RAT (13-779): 0: 1014: 71.52
+	Mm
		497913 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		PFKAL_MOUSE (19-779): 0: 1023: 69.42
+	Mm
		497944 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		PFKAM_MOUSE (13-779): 0: 1023: 72.04
+	Hs
		496252 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03