HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: EF1A2 (Q05639)
Elongation factor 1-alpha 2 (EF-1-alpha-2) (Eukaryotic elongation factor 1 A-2) (eEF1A-2) (Statin-S1)
Gene: EEF1A2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	35063084, 26402096, 26269332
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0019901 - protein kinase binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 463
+	Hs
		496815 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		EF1A1_HUMAN (1-462): 0: 558: 92.42
+	Hs
		497171 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		EF1A3_HUMAN (1-462): 0: 555: 91.99
+	Rn
		581966 TAU_RAT (1-758): 4.86e-75: 260: 71.47		EF1A2_RAT (1-463): 0: 559: 99.78
+	Rn
		94189 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		EF1A2_RAT (1-463): 0: 559: 99.78
+	Mm
		486083 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		EF1A1_MOUSE (1-462): 0: 558: 92.21
+	Hs
		496223 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ERF3A_HUMAN (2-444): 1.97e-157: 457: 36.26
+	Hs
		497278 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ERF3B_HUMAN (2-444): 3.45e-155: 456: 35.81
+	Dm
		1369275 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VK85_DROME (4-443): 1.14e-151: 446: 36.28