HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 793
+	Hs
		497371 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		496439 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH10_HUMAN (55-788): 1.22e-26: 119: 10.63
+	Hs
		497876 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYO5A_HUMAN (42-632): 2.15e-24: 112: 15.29
+	Hs
		254438 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROCK2_HUMAN (1-685): 2.36e-23: 108: 9.77
+	Hs
		496228 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DESP_HUMAN (13-640): 3.03e-22: 105: 14.35
+	Hs
		496438 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		497051 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94
+	Rn
		582036 TAU_RAT (1-758): 4.86e-75: 260: 71.47		MYH10_RAT (55-785): 3.7e-26: 117: 10.67
+	Rn
		94262 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		MYH10_RAT (55-785): 3.7e-26: 117: 10.67
+	Hs
		496834 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MAP1A_HUMAN (212-642): 6.08e-13: 75: 18.04
+	Hs
		497209 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		WDR87_HUMAN (5-627): 1.51e-11: 70.6: 11.11
+	Hs
		497642 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		503287 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94
+	Hs
		148818 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		203228 SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76		ITSN1_HUMAN (235-636): 6.18e-27: 120: 21.34
+	Hs
		149481 PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Dm
		1370292 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VTY8_DROME (26-625): 3.37e-10: 65.9: 12.21
+	Dm
		54892 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		A1ZA72_DROME (138-632): 5.06e-09: 62.2: 17.72
+	Dm
		116377 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		M9PI41_DROME (26-625): 3.38e-10: 65.9: 12.21
+	Dm
		973540 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		Q9VTY8_DROME (26-625): 3.37e-10: 65.9: 12.21