HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PRDX1 (Q06830)
Peroxiredoxin-1 (EC 1.11.1.24) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Thioredoxin-dependent peroxiredoxin 1)
Gene: PRDX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 199
+	Hs
		496419 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRDX2_HUMAN (1-198): 2.38e-103: 297: 77.78
+	Hs
		496385 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRDX3_HUMAN (2-197): 1.85e-98: 287: 62.76
+	Hs
		496950 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRDX4_HUMAN (4-197): 4.03e-95: 279: 69.59
+	Mm
		498041 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		PRDX2_MOUSE (1-198): 1.73e-103: 298: 76.26
+	Hs
		496383 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRDX6_HUMAN (4-197): 5.84e-67: 206: 28.50
+	Mm
		139700 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		PRDX6_MOUSE (4-197): 1.21e-68: 210: 29.47
+	Dm
		1358961 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		PRDX2_DROME (7-196): 2.15e-93: 272: 71.05