HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CKAP4 (Q07065)
Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63)
Gene: CKAP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36634849, 35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 602
+	Hs
		497239 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH14_HUMAN (127-597): 5.01e-26: 116: 13.49
+	Hs
		496439 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH10_HUMAN (175-601): 2.98e-20: 98: 10.72
+	Hs
		497769 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH2_HUMAN (21-600): 1.19e-18: 92.6: 9.43
+	Hs
		496438 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78
+	Hs
		496396 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CLIP1_HUMAN (135-600): 1.12e-09: 63.8: 15.06
+	Rn
		582036 TAU_RAT (1-758): 4.86e-75: 260: 71.47		MYH10_RAT (37-562): 5.25e-20: 97.2: 11.89
+	Rn
		94262 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		MYH10_RAT (37-562): 5.25e-20: 97.2: 11.89
+	Hs
		1056879 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		MYH14_HUMAN (127-597): 5.01e-26: 116: 13.49
+	Hs
		148818 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03
+	Hs
		654047 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		FYCO1_HUMAN (130-602): 7.66e-11: 67.5: 21.11
+	Hs
		654019 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47
+	Hs
		149481 PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19		CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03
+	Ce
		136787 UNC89_CAEEL (4-459): 4.47e-21: 101: 12.37		MYSP_CAEEL (128-576): 1e-09: 63.7: 19.17