HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: DEMA (Q08495)
Dematin (Dematin actin-binding protein) (Erythrocyte membrane protein band 4.9)
Gene: DMTN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 405
+	Hs
		150508 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ABLM1_HUMAN (2-405): 7.68e-140: 419: 40.44
+	Hs
		497180 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ABLM2_HUMAN (2-405): 1.04e-124: 375: 28.57
+	Hs
		300985 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ABLM3_HUMAN (2-405): 1.47e-101: 317: 33.33
+	Hs
		171263 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		VILL_HUMAN (57-405): 7.73e-69: 234: 12.85
+	Hs
		413811 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GELS_HUMAN (42-299): 1.42e-48: 177: 9.67