HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: KIF1A (Q12756)
Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles) (Microtubule-based motor KIF1A) (Unc-104- and KIF1A-related protein) (hUnc-104)
Gene: KIF1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005874 - microtubule GO:0008017 - microtubule binding GO:0030424 - axon GO:0030425 - dendrite GO:1904115 - axon cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1690
+	Hs
		216897 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF1C_HUMAN (1-856): 1.17e-148: 488: 57.72
+	Hs
		166357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF3B_HUMAN (2-471): 1.44e-150: 482: 36.29
+	Hs
		497243 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KI21A_HUMAN (3-1135): 1.69e-126: 437: 19.08
+	Hs
		496931 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF5A_HUMAN (3-945): 3.86e-120: 406: 21.80
+	Ce
		109403 H2KY94_CAEEL (465-688): 3.39e-25: 107: 33.48		UN104_CAEEL (4-915): 4.73e-168: 553: 57.30
+	Hs
		1056837 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		KIF14_HUMAN (1-818): 5.53e-114: 400: 35.27
+	Hs
		1066964 PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19		KIF14_HUMAN (1-818): 5.53e-114: 400: 35.27
+	Hs
		496422 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KINH_HUMAN (663-1081): 5.96e-15: 82.7: 9.31
+	Hs
		229832 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF5C_HUMAN (756-1099): 3.87e-12: 73.8: 7.54
+	Hs
		253242 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KI21B_HUMAN (676-1156): 8.71e-12: 72.6: 9.13
+	Hs
		497871 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF3A_HUMAN (810-1042): 5.84e-09: 63: 5.15