HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: KIF5A (Q12840)
Kinesin heavy chain isoform 5A (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC)
Gene: KIF5A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32812023
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005874 - microtubule GO:0008017 - microtubule binding GO:1904115 - axon cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1032
+	Hs
		166357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF3B_HUMAN (1-567): 4.42e-146: 455: 32.83
+	Hs
		496927 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF1A_HUMAN (6-641): 2.05e-108: 373: 24.15
+	Hs
		111250 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		J3KNA1_HUMAN (118-1032): 1.09e-101: 343: 98.58
+	Hs
		216897 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF1C_HUMAN (6-668): 1.81e-96: 332: 23.86
+	Hs
		653940 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		KIF11_HUMAN (2-876): 1.97e-155: 489: 27.47
+	Hs
		91550 E7EVA0_HUMAN (217-742): 5.43e-26: 117: 24.87		KIF11_HUMAN (2-876): 1.97e-155: 489: 27.47
+	Ce
		109403 H2KY94_CAEEL (465-688): 3.39e-25: 107: 33.48		UN104_CAEEL (7-708): 6.31e-105: 362: 24.73
+	Hs
		229832 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20
+	Hs
		496422 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45
+	Hs
		2882 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		A0A0G2JMZ6_HUMAN (477-1017): 8.8e-14: 77.9: 10.69
+	Hs
		253242 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KI21B_HUMAN (250-858): 1.93e-10: 67.5: 10.51
+	Hs
		497243 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KI21A_HUMAN (243-875): 2.22e-10: 67.2: 10.00
+	Hs
		497871 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF3A_HUMAN (510-750): 5.1e-09: 62.5: 13.15