HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ECH1 (Q13011)
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-)
Gene: ECH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36634849, 35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 328
+	Hs
		496388 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ECHM_HUMAN (27-322): 3.57e-91: 275: 24.66
+	Hs
		496484 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ECHA_HUMAN (70-246): 5.11e-15: 77.8: 31.87
+	Rn
		582012 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ECHA_RAT (70-246): 1.11e-20: 94.7: 35.91
+	Rn
		94237 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ECHA_RAT (70-246): 1.11e-20: 94.7: 35.91