HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PSMD2 (Q13200)
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
Gene: PSMD2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.687

Property	Details
Experiments	32357304, 32812023, 26269332, 35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 908
+	Rn
		582000 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PSMD2_RAT (1-908): 0: 1272: 98.57
+	Rn
		94222 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PSMD2_RAT (1-908): 0: 1272: 98.57
+	Dm
		1370317 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VW54_DROME (3-906): 0: 1063: 60.65
+	Hs
		497481 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PSMD1_HUMAN (59-845): 0: 790: 17.31