Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.699

The method score is based on:

Property Details
Experiments 27070645, 24905733, 24251416, 26269332, 35063084
Identification Methods pull down, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000226 - microtubule cytoskeleton organization
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005874 - microtubule
GO:0015630 - microtubule cytoskeleton
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 758
Hs

1 450
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024