HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: DCTN2 (Q13561)
Dynactin subunit 2 (50 kDa dynein-associated polypeptide) (Dynactin complex 50 kDa subunit) (DCTN-50) (p50 dynamitin)
Gene: DCTN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26269332, 21339331, 35063084
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005874 - microtubule GO:0019901 - protein kinase binding GO:0030426 - growth cone
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 401
+	Rn
		582017 TAU_RAT (1-758): 4.86e-75: 260: 71.47		DCTN2_RAT (1-401): 0: 531: 95.52
+	Rn
		94243 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		DCTN2_RAT (1-401): 0: 531: 95.52
+	Mm
		498114 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		DCTN2_MOUSE (1-401): 0: 536: 95.52