HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: FHL1 (Q13642)
Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM-protein 1) (SLIM) (SLIM-1)
Gene: FHL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	32812023, 35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 323
+	Hs
		1056958 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		ZN251_HUMAN (22-317): 8.15e-88: 278: 11.96
+	Hs
		496537 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		LIMS1_HUMAN (98-240): 6.01e-25: 104: 24.67
+	Hs
		497180 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ABLM2_HUMAN (97-239): 3.89e-22: 98.9: 21.29
+	Hs
		1044538 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		FHL1_HUMAN (1-323): 7.74e-90: 272: 100.00
+	Hs
		150508 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ABLM1_HUMAN (126-268): 7.44e-18: 86.2: 22.07
+	Hs
		497153 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		Q5JXI8_HUMAN (2-72): 1.32e-10: 62.7: 33.78
+	Hs
		1056987 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		ZN768_HUMAN (129-293): 9.95e-34: 131: 16.77
+	Ce
		136803 UNC89_CAEEL (4-459): 4.47e-21: 101: 12.37		Q3S1I9_CAEEL (57-229): 1.15e-41: 147: 30.29
+	Dm
		973530 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		Q2PDT4_DROME (100-250): 3.95e-43: 158: 29.41
+	Dm
		973532 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		Q8INW7_DROME (100-250): 1.41e-42: 156: 29.41
+	Hs
		1050839 MAGL2_HUMAN (1-739): 1.99e-19: 95.9: 10.23		FHL2_HUMAN (3-92): 4.15e-15: 76.2: 34.78
+	Ce
		107557 UNC89_CAEEL (4-459): 4.47e-21: 101: 12.37		G5EFG1_CAEEL (98-228): 1.38e-10: 64.3: 27.82