HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CD166 (Q13740)
CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166)
Gene: ALCAM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030424 - axon GO:0030425 - dendrite GO:0043025 - neuronal cell body
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 583
+	Hs
		297882 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NFASC_HUMAN (18-553): 1.11e-46: 178: 11.71
+	Hs
		496195 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NCAM1_HUMAN (24-527): 6.57e-42: 163: 13.02
+	Hs
		496932 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CNTN1_HUMAN (350-583): 2.56e-21: 100: 11.11
+	Hs
		497552 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CADM1_HUMAN (259-493): 5.61e-20: 94.9: 19.64
+	Hs
		497325 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CADM4_HUMAN (252-575): 6.18e-20: 94.2: 19.67
+	Hs
		497288 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CADM3_HUMAN (256-493): 1.21e-18: 90.3: 17.99
+	Hs
		497905 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROBO1_HUMAN (385-580): 1.75e-17: 89: 11.54
+	Hs
		497622 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROBO2_HUMAN (15-467): 3.02e-16: 84.7: 12.06
+	Hs
		497294 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CADM2_HUMAN (114-395): 2.45e-16: 83.4: 14.78
+	Hs
		497357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TITIN_HUMAN (45-566): 6.99e-10: 64.7: 10.66
+	Mm
		497914 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		CNTN1_MOUSE (350-583): 3.03e-21: 100: 10.71