HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: DPYL1 (Q14194)
Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response mediator protein 1) (CRMP-1) (Inactive dihydropyrimidinase) (Unc-33-like phosphoprotein 3) (ULIP-3)
Gene: CRMP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030426 - growth cone
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 572
+	Hs
		497102 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DPYL2_HUMAN (1-572): 0: 764: 76.22
+	Hs
		147310 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DPYL4_HUMAN (1-571): 0: 748: 69.18
+	Hs
		497006 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DPYL3_HUMAN (1-571): 0: 748: 74.43
+	Rn
		582008 TAU_RAT (1-758): 4.86e-75: 260: 71.47		DPYL1_RAT (1-572): 0: 769: 96.68
+	Rn
		94232 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		DPYL1_RAT (1-572): 0: 769: 96.68
+	Rn
		581948 TAU_RAT (1-758): 4.86e-75: 260: 71.47		DPYL2_RAT (1-572): 0: 762: 76.40
+	Rn
		94172 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		DPYL2_RAT (1-572): 0: 762: 76.40
+	Mm
		498057 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		DPYL3_MOUSE (1-571): 0: 747: 74.08
+	Hs
		497508 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DPYL5_HUMAN (14-567): 0: 656: 50.90