HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: MAP7 (Q14244)
Ensconsin (Epithelial microtubule-associated protein of 115 kDa) (E-MAP-115) (Microtubule-associated protein 7) (MAP-7)
Gene: MAP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005829 - cytosol GO:0005874 - microtubule GO:0015630 - microtubule cytoskeleton GO:0030424 - axon
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 749
+	Rn
		582007 TAU_RAT (1-758): 4.86e-75: 260: 71.47		SYNJ1_RAT (170-733): 1.07e-61: 227: 12.08
+	Rn
		94231 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		SYNJ1_RAT (170-733): 1.07e-61: 227: 12.08
+	Hs
		497126 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MA7D1_HUMAN (20-682): 5.64e-49: 187: 30.17
+	Hs
		497383 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CBP_HUMAN (71-604): 3.5e-46: 180: 15.57
+	Hs
		203203 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SYNJ1_HUMAN (117-733): 2.19e-42: 168: 10.45
+	Hs
		497474 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MA7D2_HUMAN (26-681): 1.97e-39: 157: 24.54
+	Mm
		88453 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		D3Z656_MOUSE (117-734): 3.81e-50: 192: 9.49
+	Hs
		496652 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AFAD_HUMAN (112-729): 1.82e-27: 121: 12.28
+	Hs
		496871 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ANK2_HUMAN (65-618): 3.44e-25: 114: 12.28
+	Hs
		496924 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		EP300_HUMAN (71-604): 1.01e-24: 113: 14.26
+	Hs
		497766 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TNIK_HUMAN (31-501): 3.32e-24: 111: 14.14
+	Rn
		193551 TAU_RAT (1-758): 4.86e-75: 260: 71.47		AFAD_RAT (112-729): 2.09e-34: 144: 11.74
+	Rn
		94105 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		AFAD_RAT (112-729): 2.09e-34: 144: 11.74
+	Hs
		497051 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PLEC_HUMAN (430-636): 7.37e-13: 74.9: 20.83
+	Hs
		497357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TITIN_HUMAN (68-741): 1.24e-11: 70.9: 8.66
+	Hs
		496432 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MERL_HUMAN (476-620): 3.55e-10: 65.4: 24.66
+	Rn
		562615 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NFH_RAT (330-748): 3.47e-14: 78.6: 9.52
+	Rn
		94083 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		F1LRZ7_RAT (339-748): 3.77e-13: 75.5: 10.71
+	Hs
		653964 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		EP300_HUMAN (71-604): 1.01e-24: 113: 14.26
+	Dm
		54348 A1Z9J3_DROME (14-746): 5.58e-33: 139: 11.47		Q9W053_DROME (476-583): 8.66e-09: 61.6: 23.15