HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ACAP2 (Q15057)
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)
Gene: ACAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:1990090 - cellular response to nerve growth factor stimulus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 778
+	Hs
		497809 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AGAP1_HUMAN (300-634): 6.59e-24: 109: 22.85
+	Hs
		195781 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ASAP2_HUMAN (132-729): 4.36e-16: 85.1: 13.51
+	Hs
		497458 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AGAP3_HUMAN (607-697): 5.24e-12: 71.8: 29.03
+	Hs
		1243507 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		DP13B_HUMAN (4-370): 2.6e-70: 245: 24.02
+	Dm
		1342084 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		CEG1A_DROME (330-585): 8.59e-27: 119: 30.04
+	Mm
		88454 D3Z656_MOUSE (72-555): 1.33e-11: 70.4: 11.56		AGAP2_MOUSE (632-698): 3.64e-12: 72.2: 28.36
+	Mm
		1112664 PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66		AGAP2_MOUSE (632-698): 3.64e-12: 72.2: 28.36