HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RAB35 (Q15286)
Ras-related protein Rab-35 (GTP-binding protein RAY) (Ras-related protein Rab-1C)
Gene: RAB35

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0031175 - neuron projection development GO:1990090 - cellular response to nerve growth factor stimulus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 201
+	Hs
		496764 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1A_HUMAN (1-201): 5.61e-88: 258: 53.96
+	Hs
		497581 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1B_HUMAN (1-201): 6.61e-86: 253: 53.96
+	Hs
		497392 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB8B_HUMAN (1-199): 1.64e-82: 245: 47.50
+	Hs
		496754 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB11A_HUMAN (2-201): 1.19e-79: 238: 40.67
+	Mm
		497979 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1A_MOUSE (1-201): 5.61e-88: 258: 53.96
+	Mm
		498132 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1B_MOUSE (1-201): 1.73e-85: 252: 53.47
+	Hs
		496594 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB13_HUMAN (1-169): 1.35e-62: 194: 55.29
+	Hs
		496696 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB10_HUMAN (3-201): 5.3e-62: 192: 47.50
+	Mm
		497961 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB10_MOUSE (3-201): 5.3e-62: 192: 47.50
+	Hs
		297829 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		RAB35_HUMAN (1-201): 2.42e-84: 249: 100.00