HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PCBP2 (Q15366)
Poly(rC)-binding protein 2 (Alpha-CP2) (Heterogeneous nuclear ribonucleoprotein E2) (hnRNP E2)
Gene: PCBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003697 - single-stranded DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0019899 - enzyme binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 365
+	Mm
		498053 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		PCBP2_MOUSE (1-365): 1.69e-112: 333: 98.36
+	Hs
		496726 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRPK_HUMAN (10-361): 2.75e-76: 244: 26.17
+	Mm
		497970 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Hs
		497393 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FUBP2_HUMAN (282-364): 1.14e-16: 83.3: 30.12
+	Hs
		497407 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FUBP1_HUMAN (216-362): 1.11e-13: 74.1: 19.73
+	Hs
		497064 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PCBP1_HUMAN (93-173): 3.7e-12: 68.7: 28.40
+	Mm
		497959 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		PCBP1_MOUSE (93-173): 3.7e-12: 68.7: 28.40
+	Mm
		497957 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		PCBP3_MOUSE (233-358): 6.19e-11: 65.2: 22.22
+	Hs
		1056915 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		FUBP2_HUMAN (282-364): 1.14e-16: 83.3: 30.12
+	Hs
		653982 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		PCBP1_HUMAN (93-173): 3.7e-12: 68.7: 28.40
+	Hs
		1056922 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		FUBP1_HUMAN (216-362): 1.11e-13: 74.1: 19.73