HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0017124 - SH3 domain binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 474
+	Hs
		253242 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KI21B_HUMAN (35-374): 2.35e-29: 124: 19.73
+	Hs
		497007 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02
+	Hs
		496438 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		497371 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Rn
		581930 TAU_RAT (1-758): 4.86e-75: 260: 71.47		DCTN1_RAT (7-361): 6.92e-22: 101: 13.17
+	Rn
		94152 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		DCTN1_RAT (7-361): 6.92e-22: 101: 13.17
+	Hs
		497051 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PLEC_HUMAN (67-346): 2.74e-09: 61.9: 11.79
+	Hs
		496439 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH10_HUMAN (2-333): 9.28e-09: 60.4: 10.39
+	Hs
		497769 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH2_HUMAN (27-306): 9.34e-09: 60: 9.97
+	Hs
		1056882 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		TAXB1_HUMAN (59-365): 6.01e-28: 119: 20.46
+	Hs
		203229 SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76		CCDC6_HUMAN (1-474): 2.18e-48: 174: 100.00
+	Hs
		653974 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02
+	Hs
		503286 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02
+	Hs
		503287 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		PLEC_HUMAN (67-346): 2.74e-09: 61.9: 11.79
+	Hs
		148818 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78
+	Hs
		203228 SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76		ITSN1_HUMAN (14-474): 1.6e-22: 103: 11.38
+	Hs
		149481 PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19		CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78